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Requirements for activation and RAFT localization of the T-lymphocyte kinase Rlk/Txk

BACKGROUND: The Tec family kinases are implicated in signaling from lymphocyte antigen receptors and are activated following phosphorylation by Src kinases. For most Tec kinases, this activation requires an interaction between their pleckstrin homology (PH) domains and the products of phosphoinositi...

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Detalles Bibliográficos
Autores principales: Chamorro, Mario, Czar, Michael J, Debnath, Jayanta, Cheng, Genhong, Lenardo, Michael J, Varmus, Harold E, Schwartzberg, Pamela L
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC31577/
https://www.ncbi.nlm.nih.gov/pubmed/11353545
http://dx.doi.org/10.1186/1471-2172-2-3