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Role of Pten in leukemia stem cells

Chronic myeloid leukemia (CML) is initiated from the BCR-ABL-expressing leukemia stem cells (LSCs). These LSCs are highly resistant to BCR-ABL kinase inhibitors, imatinib, dasantinib and nilotinib, and methods for eradication of LSCs are still not available. It is critical to identify genes that pla...

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Detalles Bibliográficos
Autores principales:	Peng, Cong, Chen, Yaoyu, Li, Dongguang, Li, Shaoguang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2010
Materias:	Research Perspectives
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3157706/ https://www.ncbi.nlm.nih.gov/pubmed/21297225

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