Interleukin-9 (IL-9) and NPM-ALK each generate mast cell hyperplasia as single ‘hit’ and cooperate in producing a mastocytosis-like disease in mice

Mast cell neoplasms are characterized by abnormal growth and focal accumulation of mast cells (MC) in one or more organs. Although several cytokines, including stem cell factor (SCF) and interleukin-9 (IL-9) have been implicated in growth of normal MC, little is known about pro-oncogenic molecules a...

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Detalles Bibliográficos
Autores principales: Merz, Hartmut, Kaehler, Christian, Hoefig, Kai P., Branke, Biggi, Uckert, Wolfgang, Nadrowitz, Roger, Sabine-Cerny-Reiterer, Herrmann, Harald, Feller, Alfred C., Valent, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2010
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3157709/
https://www.ncbi.nlm.nih.gov/pubmed/21297223

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