PGAT: a multistrain analysis resource for microbial genomes

Motivation: The Prokaryotic-genome Analysis Tool (PGAT) is a web-based database application for comparing gene content and sequence across multiple microbial genomes facilitating the discovery of genetic differences that may explain observed phenotypes. PGAT supports database queries to identify gen...

Descripción completa

Detalles Bibliográficos
Autores principales: Brittnacher, M. J., Fong, C., Hayden, H. S., Jacobs, M. A., Radey, Matthew, Rohmer, L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Applications Note
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3157930/
https://www.ncbi.nlm.nih.gov/pubmed/21765097
http://dx.doi.org/10.1093/bioinformatics/btr418
Descripción
Sumario:Motivation: The Prokaryotic-genome Analysis Tool (PGAT) is a web-based database application for comparing gene content and sequence across multiple microbial genomes facilitating the discovery of genetic differences that may explain observed phenotypes. PGAT supports database queries to identify genes that are present or absent in user-selected genomes, comparison of sequence polymorphisms in sets of orthologous genes, multigenome display of regions surrounding a query gene, comparison of the distribution of genes in metabolic pathways and manual community annotation. Availability and Implementation:The PGAT website may be accessed at http://nwrce.org/pgat. Contact: mbrittna@uw.edu

Ejemplares similares