Activation of HIV Transcription by the Viral Tat Protein Requires a Demethylation Step Mediated by Lysine-specific Demethylase 1 (LSD1/KDM1)

The essential transactivator function of the HIV Tat protein is regulated by multiple posttranslational modifications. Although individual modifications are well characterized, their crosstalk and dynamics of occurrence during the HIV transcription cycle remain unclear. We examine interactions betwe...

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Detalles Bibliográficos
Autores principales: Sakane, Naoki, Kwon, Hye-Sook, Pagans, Sara, Kaehlcke, Katrin, Mizusawa, Yasuhiro, Kamada, Masafumi, Lassen, Kara G., Chan, Jonathan, Greene, Warner C., Schnoelzer, Martina, Ott, Melanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3158049/
https://www.ncbi.nlm.nih.gov/pubmed/21876670
http://dx.doi.org/10.1371/journal.ppat.1002184

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3158049/
https://www.ncbi.nlm.nih.gov/pubmed/21876670
http://dx.doi.org/10.1371/journal.ppat.1002184

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