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TC-PTP Dephosphorylates the Guanine Nucleotide Exchange Factor C3G (RapGEF1) and Negatively Regulates Differentiation of Human Neuroblastoma Cells

The guanine nucleotide exchange factor, C3G (RapGEF1), functions in multiple signaling pathways involved in cell adhesion, proliferation, apoptosis and actin reorganization. C3G is regulated by tyrosine phosphorylation on Y504, known to be mediated by c-Abl and Src family kinases. In the present stu...

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Detalles Bibliográficos
Autores principales:	Mitra, Aninda, Kalayarasan, Srinivasan, Gupta, Vijay, Radha, Vegesna
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3158094/ https://www.ncbi.nlm.nih.gov/pubmed/21876762 http://dx.doi.org/10.1371/journal.pone.0023681

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