Cargando…
H5N1 Whole-Virus Vaccine Induces Neutralizing Antibodies in Humans Which Are Protective in a Mouse Passive Transfer Model
BACKGROUND: Vero cell culture-derived whole-virus H5N1 vaccines have been extensively tested in clinical trials and consistently demonstrated to be safe and immunogenic; however, clinical efficacy is difficult to evaluate in the absence of wide-spread human disease. A lethal mouse model has been uti...
Autores principales: | Howard, M. Keith, Sabarth, Nicolas, Savidis-Dacho, Helga, Portsmouth, Daniel, Kistner, Otfried, Kreil, Thomas R., Ehrlich, Hartmut J., Barrett, P. Noel |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3158096/ https://www.ncbi.nlm.nih.gov/pubmed/21876771 http://dx.doi.org/10.1371/journal.pone.0023791 |
Ejemplares similares
-
A Whole Virus Pandemic Influenza H1N1 Vaccine Is Highly Immunogenic and Protective in Active Immunization and Passive Protection Mouse Models
por: Kistner, Otfried, et al.
Publicado: (2010) -
A Pandemic Influenza H1N1 Live Vaccine Based on Modified Vaccinia Ankara Is Highly Immunogenic and Protects Mice in Active and Passive Immunizations
por: Hessel, Annett, et al.
Publicado: (2010) -
Immunogenicity and Protective Efficacy of a Vero Cell Culture-Derived Whole-Virus H7N9 Vaccine in Mice and Guinea Pigs
por: Wodal, Walter, et al.
Publicado: (2015) -
A double-inactivated whole virus candidate SARS coronavirus vaccine stimulates neutralising and protective antibody responses
por: Spruth, Martin, et al.
Publicado: (2006) -
MVA Vectors Expressing Conserved Influenza Proteins Protect Mice against Lethal Challenge with H5N1, H9N2 and H7N1 Viruses
por: Hessel, Annett, et al.
Publicado: (2014)