Dual paraneoplastic syndromes in a patient with small cell lung cancer: a case report

INTRODUCTION: We describe the case of a patient with small cell lung cancer and dual paraneoplastic syndromes involving adrenocorticotropic hormone and calcitonin. To the best of our knowledge, dual paraneoplastic syndromes involving these two hormones have not been previously reported in the litera...

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Detalles Bibliográficos
Autores principales: Coners, Kristin, Woods, Scott E, Webb, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3158120/
https://www.ncbi.nlm.nih.gov/pubmed/21771301
http://dx.doi.org/10.1186/1752-1947-5-318
Descripción
Sumario:INTRODUCTION: We describe the case of a patient with small cell lung cancer and dual paraneoplastic syndromes involving adrenocorticotropic hormone and calcitonin. To the best of our knowledge, dual paraneoplastic syndromes involving these two hormones have not been previously reported in the literature. CASE PRESENTATION: A 74-year-old Caucasian woman presented with a left hilar mass and metastatic disease in the liver and right adrenal gland. The patient complained only of intermittent diarrhea. Her laboratory values exhibited metabolic alkalosis with hypokalemia, hypocalcemia, hypomagnesemia, hypophosphatemia, and hyperglycemia. CONCLUSION: We discuss the work-up and treatment of the patient's unusual laboratory presentation with two concurrent paraneoplastic syndromes.

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