Targeting AMP-activated protein kinase in adipocytes to modulate obesity-related adipokine production associated with insulin resistance and breast cancer cell proliferation

BACKGROUND: Adipokines, e.g. TNFα, IL-6 and leptin increase insulin resistance, and consequent hyperinsulinaemia influences breast cancer progression. Beside its mitogenic effects, insulin may influence adipokine production from adipocyte stromal cells and paracrine enhancement of breast cancer cell...

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Detalles Bibliográficos
Autores principales: Grisouard, Jean, Dembinski, Kaethi, Mayer, Doris, Keller, Ulrich, Müller, Beat, Christ-Crain, Mirjam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Short Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3158545/
https://www.ncbi.nlm.nih.gov/pubmed/21774820
http://dx.doi.org/10.1186/1758-5996-3-16

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