Synthesis, Crystal Structure, and DNA-Binding Studies of a Nickel(II) Complex with the Bis(2-benzimidazolymethyl)amine Ligand

A V-shaped ligand Bis(2-benzimidazolymethyl)amine (bba) and its nickel(II) picrate (pic) complex, with composition [Ni(bba)(2)](pic)(2)·3MeOH, have been synthesized and characterized on the basis of elemental analyses, molar conductivities, IR spectra, and UV/vis measurements. In the complex, the Ni...

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Detalles Bibliográficos
Autores principales: Wu, Huilu, Sun, Tao, Li, Ke, Liu, Bin, Kou, Fan, Jia, Fei, Yuan, Jingkun, Bai, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3159005/
https://www.ncbi.nlm.nih.gov/pubmed/21876684
http://dx.doi.org/10.1155/2012/609796
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author Wu, Huilu
Sun, Tao
Li, Ke
Liu, Bin
Kou, Fan
Jia, Fei
Yuan, Jingkun
Bai, Ying
author_facet Wu, Huilu
Sun, Tao
Li, Ke
Liu, Bin
Kou, Fan
Jia, Fei
Yuan, Jingkun
Bai, Ying
author_sort Wu, Huilu
collection PubMed
description A V-shaped ligand Bis(2-benzimidazolymethyl)amine (bba) and its nickel(II) picrate (pic) complex, with composition [Ni(bba)(2)](pic)(2)·3MeOH, have been synthesized and characterized on the basis of elemental analyses, molar conductivities, IR spectra, and UV/vis measurements. In the complex, the Ni(II) ion is six-coordinated with a N(2)O(4) ligand set, resulting in a distorted octahedron coordination geometry. In addition, the DNA-binding properties of the Ni(II) complex have been investigated by electronic absorption, fluorescence, and viscosity measurements. The experimental results suggest that the nickel(II) complex binds to DNA by partial intercalation binding mode.
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spelling pubmed-31590052011-08-29 Synthesis, Crystal Structure, and DNA-Binding Studies of a Nickel(II) Complex with the Bis(2-benzimidazolymethyl)amine Ligand Wu, Huilu Sun, Tao Li, Ke Liu, Bin Kou, Fan Jia, Fei Yuan, Jingkun Bai, Ying Bioinorg Chem Appl Research Article A V-shaped ligand Bis(2-benzimidazolymethyl)amine (bba) and its nickel(II) picrate (pic) complex, with composition [Ni(bba)(2)](pic)(2)·3MeOH, have been synthesized and characterized on the basis of elemental analyses, molar conductivities, IR spectra, and UV/vis measurements. In the complex, the Ni(II) ion is six-coordinated with a N(2)O(4) ligand set, resulting in a distorted octahedron coordination geometry. In addition, the DNA-binding properties of the Ni(II) complex have been investigated by electronic absorption, fluorescence, and viscosity measurements. The experimental results suggest that the nickel(II) complex binds to DNA by partial intercalation binding mode. Hindawi Publishing Corporation 2012 2011-06-30 /pmc/articles/PMC3159005/ /pubmed/21876684 http://dx.doi.org/10.1155/2012/609796 Text en Copyright © 2012 Huilu Wu et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Wu, Huilu
Sun, Tao
Li, Ke
Liu, Bin
Kou, Fan
Jia, Fei
Yuan, Jingkun
Bai, Ying
Synthesis, Crystal Structure, and DNA-Binding Studies of a Nickel(II) Complex with the Bis(2-benzimidazolymethyl)amine Ligand
title Synthesis, Crystal Structure, and DNA-Binding Studies of a Nickel(II) Complex with the Bis(2-benzimidazolymethyl)amine Ligand
title_full Synthesis, Crystal Structure, and DNA-Binding Studies of a Nickel(II) Complex with the Bis(2-benzimidazolymethyl)amine Ligand
title_fullStr Synthesis, Crystal Structure, and DNA-Binding Studies of a Nickel(II) Complex with the Bis(2-benzimidazolymethyl)amine Ligand
title_full_unstemmed Synthesis, Crystal Structure, and DNA-Binding Studies of a Nickel(II) Complex with the Bis(2-benzimidazolymethyl)amine Ligand
title_short Synthesis, Crystal Structure, and DNA-Binding Studies of a Nickel(II) Complex with the Bis(2-benzimidazolymethyl)amine Ligand
title_sort synthesis, crystal structure, and dna-binding studies of a nickel(ii) complex with the bis(2-benzimidazolymethyl)amine ligand
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3159005/
https://www.ncbi.nlm.nih.gov/pubmed/21876684
http://dx.doi.org/10.1155/2012/609796
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