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Lifespan and Glucose Metabolism in Insulin Receptor Mutant Mice

Insulin/insulin-like growth factor type 1 signaling regulates lifespan and resistance to oxidative stress in worms, flies, and mammals. In a previous study, we revealed that insulin receptor (IR) mutant mice, which carry a homologous mutation found in the long-lived daf-2 mutant of Caenorhabditis el...

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Detalles Bibliográficos
Autores principales:	Shimizu, Takahiko, Baba, Tomonori, Ogawara, Midori, Shirasawa, Takuji
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE-Hindawi Access to Research 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3159008/ https://www.ncbi.nlm.nih.gov/pubmed/21876806 http://dx.doi.org/10.4061/2011/315640

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