NF-κB-Inducing Kinase Increases Renal Tubule Epithelial Inflammation Associated with Diabetes

The impact of increased NF-κB-inducing kinase (NIK), a key component of the NF-κB activation pathways, on diabetes-induced renal inflammation remains unknown. We overexpressed NIK wild type (NIKwt) or kinase-dead dominant negative mutants (NIKdn) in HK-2 cells and demonstrated that RelB and p52, but...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhao, Yanhua, Banerjee, Srijita, LeJeune, Wanda S., Choudhary, Sanjeev, Tilton, Ronald G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3159020/
https://www.ncbi.nlm.nih.gov/pubmed/21869881
http://dx.doi.org/10.1155/2011/192564

Ejemplares similares

Ejemplares similares