Gene Profiling of Aortic Valve Interstitial Cells under Elevated Pressure Conditions: Modulation of Inflammatory Gene Networks

The study aimed to identify mechanosensitive pathways and gene networks that are stimulated by elevated cyclic pressure in aortic valve interstitial cells (VICs) and lead to detrimental tissue remodeling and/or pathogenesis. Porcine aortic valve leaflets were exposed to cyclic pressures of 80 or 120...

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Detalles Bibliográficos
Autores principales: Warnock, James N., Nanduri, Bindu, Pregonero Gamez, Carol A., Tang, Juliet, Koback, Daniel, Muir, William M., Burgess, Shane C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE-Hindawi Access to Research 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3159021/
https://www.ncbi.nlm.nih.gov/pubmed/21876831
http://dx.doi.org/10.4061/2011/176412

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3159021/
https://www.ncbi.nlm.nih.gov/pubmed/21876831
http://dx.doi.org/10.4061/2011/176412

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