Cargando…

Gene Profiling of Aortic Valve Interstitial Cells under Elevated Pressure Conditions: Modulation of Inflammatory Gene Networks

The study aimed to identify mechanosensitive pathways and gene networks that are stimulated by elevated cyclic pressure in aortic valve interstitial cells (VICs) and lead to detrimental tissue remodeling and/or pathogenesis. Porcine aortic valve leaflets were exposed to cyclic pressures of 80 or 120...

Descripción completa

Detalles Bibliográficos
Autores principales:	Warnock, James N., Nanduri, Bindu, Pregonero Gamez, Carol A., Tang, Juliet, Koback, Daniel, Muir, William M., Burgess, Shane C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE-Hindawi Access to Research 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3159021/ https://www.ncbi.nlm.nih.gov/pubmed/21876831 http://dx.doi.org/10.4061/2011/176412

Ejemplares similares

An automated proteomic data analysis workflow for mass spectrometry
por: Pendarvis, Ken, et al.
Publicado: (2009)

TAAPP: Tiling Array Analysis Pipeline for Prokaryotes
por: Kumar, Ranjit, et al.
Publicado: (2011)

Elevated Pressures on Aortic Valve Leaflets correlate with Orientation of LVAD Outflow Graft
por: Karmonik, Christof, et al.
Publicado: (2015)

Isolation and culture of rat aortic valve interstitial cells
por: Chen, Huiqiang, et al.
Publicado: (2016)

Proteome and Membrane Fatty Acid Analyses on Oligotropha carboxidovorans OM5 Grown under Chemolithoautotrophic and Heterotrophic Conditions
por: Paul, Debarati, et al.
Publicado: (2011)

Comparison of Rapidly Proliferating, Multipotent Aortic Valve-Derived Stromal Cells and Valve Interstitial Cells in the Human Aortic Valve
por: Huang, Yuming, et al.
Publicado: (2019)

Effects of Subminimum Inhibitory Concentrations of Antibiotics on the Pasteurella multocida Proteome: A Systems Approach
por: Nanduri, Bindu, et al.
Publicado: (2008)

The transcriptional response of Pasteurella multocida to three classes of antibiotics
por: Nanduri, Bindu, et al.
Publicado: (2009)

Purinergic Signaling in Pathologic Osteogenic Differentiation of Aortic Valve Interstitial Cells from Patients with Aortic Valve Calcification
por: Klauzen, Polina, et al.
Publicado: (2023)

Functional differences in human aortic valve interstitial cells from patients with varying calcific aortic valve disease
por: Tuscher, Robin, et al.
Publicado: (2023)

Exploiting novel valve interstitial cell lines to study calcific aortic valve disease
por: Tsang, Hiu-Gwen, et al.
Publicado: (2018)

Predicting key gene related to immune infiltration and myofibroblast-like valve interstitial cells in patients with calcified aortic valve disease based on bioinformatics analysis
por: Lu, Wenyuan, et al.
Publicado: (2023)

Effects of Raloxifene on the Proliferation and Apoptosis of Human Aortic Valve Interstitial Cells
por: Fu, Zhimin, et al.
Publicado: (2016)

Lipoprotein(a) Induces Human Aortic Valve Interstitial Cell Calcification
por: Yu, Bin, et al.
Publicado: (2017)

Human and porcine aortic valve endothelial and interstitial cell isolation and characterization
por: Nehl, D., et al.
Publicado: (2023)

Anterograde Crossing of a Bicuspid Aortic Valve Through Transseptal Access to Facilitate Transcatheter Aortic Valve Implantation
por: Bawamia, Bilal, et al.
Publicado: (2021)

Comprehensive proteomic analysis of bovine spermatozoa of varying fertility rates and identification of biomarkers associated with fertility
por: Peddinti, Divyaswetha, et al.
Publicado: (2008)

Prediction of peptides observable by mass spectrometry applied at the experimental set level
por: Sanders, William S, et al.
Publicado: (2007)

Identification of novel non-coding small RNAs from Streptococcus pneumoniae TIGR4 using high-resolution genome tiling arrays
por: Kumar, Ranjit, et al.
Publicado: (2010)

RNA-Seq-based transcriptional map of the bovine respiratory disease pathogen Histophilus somni 2336
por: Kumar, Ranjit, et al.
Publicado: (2011)

Midkine Prevents Calcification of Aortic Valve Interstitial Cells via Intercellular Crosstalk
por: Zhou, Qian, et al.
Publicado: (2021)

The Pressure Is On: Implications of Blood Pressure After Aortic Valve Replacement
por: Yeoh, Julian, et al.
Publicado: (2019)

RNA-Seq Based Transcriptional Map of Bovine Respiratory Disease Pathogen “Histophilus somni 2336”
por: Kumar, Ranjit, et al.
Publicado: (2012)

Transcriptome profile of a bovine respiratory disease pathogen: Mannheimia haemolytica PHL213
por: Reddy, Joseph S, et al.
Publicado: (2012)

Impact of elevated left ventricular filling pressure on long-term outcomes after transcatheter aortic valve replacement
por: Nair, Raunak M, et al.
Publicado: (2022)

Isolation and Characterization of Primary Rat Valve Interstitial Cells: A New Model to Study Aortic Valve Calcification
por: Lin, Cui, et al.
Publicado: (2017)

Decreased Glucagon-Like Peptide-1 Is Associated With Calcific Aortic Valve Disease: GLP-1 Suppresses the Calcification of Aortic Valve Interstitial Cells
por: Xiao, Fan, et al.
Publicado: (2021)

Targeted inhibition of PTPN22 is a novel approach to alleviate osteogenic responses in aortic valve interstitial cells and aortic valve lesions in mice
por: Li, Shunyi, et al.
Publicado: (2023)

ProtQuant: a tool for the label-free quantification of MudPIT proteomics data
por: Bridges, Susan M, et al.
Publicado: (2007)

Upregulated Autophagy in Calcific Aortic Valve Stenosis Confers Protection of Valvular Interstitial Cells
por: Carracedo, Miguel, et al.
Publicado: (2019)

Inflammation and Mechanical Stress Stimulate Osteogenic Differentiation of Human Aortic Valve Interstitial Cells
por: Bogdanova, Maria, et al.
Publicado: (2018)

Sortilin enhances fibrosis and calcification in aortic valve disease by inducing interstitial cell heterogeneity
por: Iqbal, Farwah, et al.
Publicado: (2023)

Elevated blood pressure and risk of aortic valve disease: a cohort analysis of 5.4 million UK adults
por: Rahimi, Kazem, et al.
Publicado: (2018)

The role of valve interstitial cells in valve disease
por: Feng, Yang, et al.
Publicado: (2016)

Transcriptomic analysis of peritoneal cells in a mouse model of sepsis: confirmatory and novel results in early and late sepsis
por: Bhatty, Minny, et al.
Publicado: (2012)

Postprocedural Troponin Elevation and Mortality After Transcatheter Aortic Valve Implantation
por: Schindler, Matthias, et al.
Publicado: (2021)

Ultrasonic Incisions Produce Less Inflammatory Mediator Response during Early Healing than Electrosurgical Incisions
por: Nanduri, Bindu, et al.
Publicado: (2013)

Crenigacestat (LY3039478) inhibits osteogenic differentiation of human valve interstitial cells from patients with aortic valve calcification in vitro
por: Lobov, Arseniy A., et al.
Publicado: (2022)

Proteoglycan 4 is Increased in Human Calcified Aortic Valves and Enhances Valvular Interstitial Cell Calcification
por: Artiach, Gonzalo, et al.
Publicado: (2020)

Mechanism of Endoplasmic Reticulum Stress Pathway in the Osteogenic Phenotypic Transformation of Aortic Valve Interstitial Cells
por: Tao, Yiming, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_0dvcebf6qpkiefvkeehjjufa12