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Induction of human neuronal cells by defined transcription factors

Somatic cell nuclear transfer, cell fusion, or expression of lineage-specific factors have been shown to induce cell-fate changes in diverse somatic cell types(1–12). We recently observed that forced expression of a combination of three transcription factors, Brn2 (also known as Pou3f2), Ascl1, and...

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Detalles Bibliográficos
Autores principales: Pang, Zhiping P., Yang, Nan, Vierbuchen, Thomas, Ostermeier, Austin, Fuentes, Daniel R., Yang, Troy Q., Citri, Ami, Sebastiano, Vittorio, Marro, Samuele, Südhof, Thomas C., Wernig, Marius
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3159048/
https://www.ncbi.nlm.nih.gov/pubmed/21617644
http://dx.doi.org/10.1038/nature10202