Cargando…
Induction of human neuronal cells by defined transcription factors
Somatic cell nuclear transfer, cell fusion, or expression of lineage-specific factors have been shown to induce cell-fate changes in diverse somatic cell types(1–12). We recently observed that forced expression of a combination of three transcription factors, Brn2 (also known as Pou3f2), Ascl1, and...
Autores principales: | Pang, Zhiping P., Yang, Nan, Vierbuchen, Thomas, Ostermeier, Austin, Fuentes, Daniel R., Yang, Troy Q., Citri, Ami, Sebastiano, Vittorio, Marro, Samuele, Südhof, Thomas C., Wernig, Marius |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3159048/ https://www.ncbi.nlm.nih.gov/pubmed/21617644 http://dx.doi.org/10.1038/nature10202 |
Ejemplares similares
-
Direct conversion of fibroblasts to functional neurons by defined factors
por: Vierbuchen, Thomas, et al.
Publicado: (2010) -
Generation of oligodendroglial cells by direct lineage conversion
por: Yang, Nan, et al.
Publicado: (2013) -
Direct Lineage Conversions: Unnatural but useful?
por: Vierbuchen, Thomas, et al.
Publicado: (2011) -
Efficient generation of dopaminergic induced neuronal cells with midbrain characteristics
por: Ng, Yi Han, et al.
Publicado: (2021) -
Conditional deletion of L1CAM in human neurons impairs both axonal and dendritic arborization and action potential generation
por: Patzke, Christopher, et al.
Publicado: (2016)