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Is it time to recast the principles of antimicrobial prophylaxis?

Perioperative antimicrobial prophylaxis has been a time-honored principle in the prevention of surgical site infection. Its effectiveness has recently been questioned. Potential reasons for the lack of demonstrable efficacy and suggestions for re-examination of this concept are presented.

Detalles Bibliográficos
Autor principal: Malangoni, Mark A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3159101/
https://www.ncbi.nlm.nih.gov/pubmed/21791052
http://dx.doi.org/10.1186/1749-7922-6-21
Descripción
Sumario:Perioperative antimicrobial prophylaxis has been a time-honored principle in the prevention of surgical site infection. Its effectiveness has recently been questioned. Potential reasons for the lack of demonstrable efficacy and suggestions for re-examination of this concept are presented.