miRTour: Plant miRNA and target prediction tool

MicroRNAs (miRNAs) are important negative regulators of gene expression in plant and animals, which are endogenously produced from their own genes. Computational comparative approach based on evolutionary conservation of mature miRNAs has revealed a number of orthologs of known miRNAs in different p...

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Detalles Bibliográficos
Autores principales: Milev, Ivan, Yahubyan, Galina, Minkov, Ivan, Baev, Vesselin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Biomedical Informatics 2011
Materias:
Web Server
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3159147/
https://www.ncbi.nlm.nih.gov/pubmed/21887016
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author Milev, Ivan
Yahubyan, Galina
Minkov, Ivan
Baev, Vesselin
author_facet Milev, Ivan
Yahubyan, Galina
Minkov, Ivan
Baev, Vesselin
author_sort Milev, Ivan
collection PubMed
description MicroRNAs (miRNAs) are important negative regulators of gene expression in plant and animals, which are endogenously produced from their own genes. Computational comparative approach based on evolutionary conservation of mature miRNAs has revealed a number of orthologs of known miRNAs in different plant species. The homology-based plant miRNA discovery, followed by target prediction, comprises several steps, which have been done so far manually. Here, we present the bioinformatics pipeline miRTour which automates all the steps of miRNA similarity search, miRNA precursor selection, target prediction and annotation, each of them performed with the same set of input sequences. AVAILABILITY: The database is available for free at http://bio2server.bioinfo.uni-plovdiv.bg/miRTour/
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spelling pubmed-31591472011-09-01 miRTour: Plant miRNA and target prediction tool Milev, Ivan Yahubyan, Galina Minkov, Ivan Baev, Vesselin Bioinformation Web Server MicroRNAs (miRNAs) are important negative regulators of gene expression in plant and animals, which are endogenously produced from their own genes. Computational comparative approach based on evolutionary conservation of mature miRNAs has revealed a number of orthologs of known miRNAs in different plant species. The homology-based plant miRNA discovery, followed by target prediction, comprises several steps, which have been done so far manually. Here, we present the bioinformatics pipeline miRTour which automates all the steps of miRNA similarity search, miRNA precursor selection, target prediction and annotation, each of them performed with the same set of input sequences. AVAILABILITY: The database is available for free at http://bio2server.bioinfo.uni-plovdiv.bg/miRTour/ Biomedical Informatics 2011-06-06 /pmc/articles/PMC3159147/ /pubmed/21887016 Text en © 2011 Biomedical Informatics This is an open-access article, which permits unrestricted use, distribution, and reproduction in any medium, for non-commercial purposes, provided the original author and source are credited.
spellingShingle Web Server
Milev, Ivan
Yahubyan, Galina
Minkov, Ivan
Baev, Vesselin
miRTour: Plant miRNA and target prediction tool
title miRTour: Plant miRNA and target prediction tool
title_full miRTour: Plant miRNA and target prediction tool
title_fullStr miRTour: Plant miRNA and target prediction tool
title_full_unstemmed miRTour: Plant miRNA and target prediction tool
title_short miRTour: Plant miRNA and target prediction tool
title_sort mirtour: plant mirna and target prediction tool
topic Web Server
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3159147/
https://www.ncbi.nlm.nih.gov/pubmed/21887016
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AT minkovivan mirtourplantmirnaandtargetpredictiontool
AT baevvesselin mirtourplantmirnaandtargetpredictiontool

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