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Preparation and Characterization of Metformin Hydrochloride — Compritol 888 ATO Solid Dispersion
Metformin hydrochloride (MET) sustained-release solid dispersions (SD) were prepared by the solvent evaporation and closed melt method, using compritol 888 ATO as the polymer with five different drug-carrier ratios. Characterization of solid dispersion was carried out by Fourier Transform Infrared (...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3159272/ https://www.ncbi.nlm.nih.gov/pubmed/21897658 http://dx.doi.org/10.4103/0975-1483.83758 |