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Preparation and Evaluation of Silymarin β-cyclodextrin Molecular Inclusion Complexes
Silymarin is a hepatoprotective agent, having poor water solubility and oral absorption of about 23 – 47%, leading to low bioavailability of the drug. The aim of the present study is to improve the solubility and dissolution rate and in turn the hepatoprotective activity of the drug, by formulating...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3159273/ https://www.ncbi.nlm.nih.gov/pubmed/21897659 http://dx.doi.org/10.4103/0975-1483.83759 |