Studies on the Anthelmintic Property of Aminobenzylated Mannich Bases

Studies were conducted on the anthelmintic property of about 15(e-h, 1e-1h, 2d-2f and 3e-3h) synthesized aminobenzylated Mannich bases bearing N-methyl piperazine using Indian earthworms Pheritima Posthuma against piperazine citrate as standard reference. Three concentrations of each compound (0.1,...

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Detalles Bibliográficos
Autores principales: Chaluvaraju, KC, Bhat, KI
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications 2011
Materias:
Pharmaceutical Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3159280/
https://www.ncbi.nlm.nih.gov/pubmed/21897666
http://dx.doi.org/10.4103/0975-1483.83775
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author Chaluvaraju, KC
Bhat, KI
author_facet Chaluvaraju, KC
Bhat, KI
author_sort Chaluvaraju, KC
collection PubMed
description Studies were conducted on the anthelmintic property of about 15(e-h, 1e-1h, 2d-2f and 3e-3h) synthesized aminobenzylated Mannich bases bearing N-methyl piperazine using Indian earthworms Pheritima Posthuma against piperazine citrate as standard reference. Three concentrations of each compound (0.1, 0.2, 0.3% w/v) were studied, which involved the determination of paralysis and death time of the worms. The compound 1g exhibited the most significant anthelmintic activity among all the compounds screened against the worms as compared to standard drug.
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spelling pubmed-31592802011-09-06 Studies on the Anthelmintic Property of Aminobenzylated Mannich Bases Chaluvaraju, KC Bhat, KI J Young Pharm Pharmaceutical Chemistry Studies were conducted on the anthelmintic property of about 15(e-h, 1e-1h, 2d-2f and 3e-3h) synthesized aminobenzylated Mannich bases bearing N-methyl piperazine using Indian earthworms Pheritima Posthuma against piperazine citrate as standard reference. Three concentrations of each compound (0.1, 0.2, 0.3% w/v) were studied, which involved the determination of paralysis and death time of the worms. The compound 1g exhibited the most significant anthelmintic activity among all the compounds screened against the worms as compared to standard drug. Medknow Publications 2011 /pmc/articles/PMC3159280/ /pubmed/21897666 http://dx.doi.org/10.4103/0975-1483.83775 Text en © Journal of Young Pharmacists http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Pharmaceutical Chemistry
Chaluvaraju, KC
Bhat, KI
Studies on the Anthelmintic Property of Aminobenzylated Mannich Bases
title Studies on the Anthelmintic Property of Aminobenzylated Mannich Bases
title_full Studies on the Anthelmintic Property of Aminobenzylated Mannich Bases
title_fullStr Studies on the Anthelmintic Property of Aminobenzylated Mannich Bases
title_full_unstemmed Studies on the Anthelmintic Property of Aminobenzylated Mannich Bases
title_short Studies on the Anthelmintic Property of Aminobenzylated Mannich Bases
title_sort studies on the anthelmintic property of aminobenzylated mannich bases
topic Pharmaceutical Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3159280/
https://www.ncbi.nlm.nih.gov/pubmed/21897666
http://dx.doi.org/10.4103/0975-1483.83775
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