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Relapsing acute myeloid leukemia presenting as hypopyon uveitis
Anterior segment infiltration in acute myeloid leukemia (AML) presenting as hypopyon uveitis is very rare. We report this case as an uncommon presentation in a patient on remission after bone marrow transplant for AML. In addition to the hypopyon, the patient presented with “red eye” caused by ocula...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3159326/ https://www.ncbi.nlm.nih.gov/pubmed/21836350 http://dx.doi.org/10.4103/0301-4738.83621 |
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author | Hegde, Sapna P Ursekar, Atul T Chitale, Ajay A |
author_facet | Hegde, Sapna P Ursekar, Atul T Chitale, Ajay A |
author_sort | Hegde, Sapna P |
collection | PubMed |
description | Anterior segment infiltration in acute myeloid leukemia (AML) presenting as hypopyon uveitis is very rare. We report this case as an uncommon presentation in a patient on remission after bone marrow transplant for AML. In addition to the hypopyon, the patient presented with “red eye” caused by ocular surface disease due to concurrent graft-versus-host disease and glaucoma. The classical manifestations of masquerade syndrome due to AML were altered by concurrent pathologies. Media opacities further confounded the differential diagnosis. We highlight the investigations used to arrive at a definitive diagnosis. In uveitis, there is a need to maintain a high index of clinical suspicion, as early diagnosis in ocular malignancy can save sight and life. |
format | Online Article Text |
id | pubmed-3159326 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2011 |
publisher | Medknow Publications |
record_format | MEDLINE/PubMed |
spelling | pubmed-31593262011-09-07 Relapsing acute myeloid leukemia presenting as hypopyon uveitis Hegde, Sapna P Ursekar, Atul T Chitale, Ajay A Indian J Ophthalmol Brief Communications Anterior segment infiltration in acute myeloid leukemia (AML) presenting as hypopyon uveitis is very rare. We report this case as an uncommon presentation in a patient on remission after bone marrow transplant for AML. In addition to the hypopyon, the patient presented with “red eye” caused by ocular surface disease due to concurrent graft-versus-host disease and glaucoma. The classical manifestations of masquerade syndrome due to AML were altered by concurrent pathologies. Media opacities further confounded the differential diagnosis. We highlight the investigations used to arrive at a definitive diagnosis. In uveitis, there is a need to maintain a high index of clinical suspicion, as early diagnosis in ocular malignancy can save sight and life. Medknow Publications 2011 /pmc/articles/PMC3159326/ /pubmed/21836350 http://dx.doi.org/10.4103/0301-4738.83621 Text en Copyright: © Indian Journal of Ophthalmology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Brief Communications Hegde, Sapna P Ursekar, Atul T Chitale, Ajay A Relapsing acute myeloid leukemia presenting as hypopyon uveitis |
title | Relapsing acute myeloid leukemia presenting as hypopyon uveitis |
title_full | Relapsing acute myeloid leukemia presenting as hypopyon uveitis |
title_fullStr | Relapsing acute myeloid leukemia presenting as hypopyon uveitis |
title_full_unstemmed | Relapsing acute myeloid leukemia presenting as hypopyon uveitis |
title_short | Relapsing acute myeloid leukemia presenting as hypopyon uveitis |
title_sort | relapsing acute myeloid leukemia presenting as hypopyon uveitis |
topic | Brief Communications |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3159326/ https://www.ncbi.nlm.nih.gov/pubmed/21836350 http://dx.doi.org/10.4103/0301-4738.83621 |
work_keys_str_mv | AT hegdesapnap relapsingacutemyeloidleukemiapresentingashypopyonuveitis AT ursekaratult relapsingacutemyeloidleukemiapresentingashypopyonuveitis AT chitaleajaya relapsingacutemyeloidleukemiapresentingashypopyonuveitis |