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Perfluorochemical Liquid-Adenovirus Suspensions Enhance Gene Delivery to the Distal Lung

We compared lung delivery methods of recombinant adenovirus (rAd): (1) rAd suspended in saline, (2) rAd suspended in saline followed by a pulse-chase of a perfluorochemical (PFC) liquid mixture, and (3) a PFC-rAd suspension. Cell uptake, distribution, and temporal expression of rAd were examined usi...

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Detalles Bibliográficos
Autores principales:	Kazzaz, Jeffrey A., Strayer, Marlene S., Wu, Jichuan, Malone, Daniel J., Koo, Hshi-chi, Shaffer, Thomas H., Davis, Jonathan M., Strayer, David S., Wolfson, Marla R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3159382/ https://www.ncbi.nlm.nih.gov/pubmed/21876799 http://dx.doi.org/10.1155/2011/918036

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