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A genetically humanized mouse model for hepatitis C virus infection

Hepatitis C virus (HCV) remains a major medical problem. Antiviral treatment is only partially effective and a vaccine does not exist. Development of more effective therapies has been hampered by the lack of a suitable small animal model. While xenotransplantation of immunodeficient mice with human...

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Detalles Bibliográficos
Autores principales: Dorner, Marcus, Horwitz, Joshua A., Robbins, Justin B., Barry, Walter T., Feng, Qian, Mu, Kathy, Jones, Christopher T., Schoggins, John W., Catanese, Maria Teresa, Burton, Dennis R., Law, Mansun, Rice, Charles M., Ploss, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3159410/
https://www.ncbi.nlm.nih.gov/pubmed/21654804
http://dx.doi.org/10.1038/nature10168