An RNA aptamer perturbs heat shock transcription factor activity in Drosophila melanogaster

Heat shock transcription factor (HSF1) is a conserved master regulator that orchestrates the protection of normal cells from stress. However, HSF1 also protects abnormal cells and is required for carcinogenesis. Here, we generate an highly specific RNA aptamer (iaRNA(HSF1)) that binds Drosophila HSF...

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Detalles Bibliográficos
Autores principales: Salamanca, H. Hans, Fuda, Nicholas, Shi, Hua, Lis, John T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3159435/
https://www.ncbi.nlm.nih.gov/pubmed/21576228
http://dx.doi.org/10.1093/nar/gkr206

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3159435/
https://www.ncbi.nlm.nih.gov/pubmed/21576228
http://dx.doi.org/10.1093/nar/gkr206

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