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Coordinated regulation of mitochondrial topoisomerase IB with mitochondrial nuclear encoded genes and MYC

Mitochondrial DNA (mtDNA) is entirely dependent on nuclear genes for its transcription and replication. One of these genes is TOP1MT, which encodes the mitochondrial DNA topoisomerase IB, involved in mtDNA relaxation. To elucidate TOP1MT regulation, we performed genome-wide profiling across the 60-c...

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Detalles Bibliográficos
Autores principales:	Zoppoli, Gabriele, Douarre, Céline, Dalla Rosa, Ilaria, Liu, Hongfang, Reinhold, William, Pommier, Yves
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2011
Materias:	Molecular Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3159436/ https://www.ncbi.nlm.nih.gov/pubmed/21531700 http://dx.doi.org/10.1093/nar/gkr208

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