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Stimulation of stop codon readthrough: frequent presence of an extended 3′ RNA structural element

In Sindbis, Venezuelan equine encephalitis and related alphaviruses, the polymerase is translated as a fusion with other non-structural proteins via readthrough of a UGA stop codon. Surprisingly, earlier work reported that the signal for efficient readthrough comprises a single cytidine residue 3′-a...

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Detalles Bibliográficos
Autores principales: Firth, Andrew E., Wills, Norma M., Gesteland, Raymond F., Atkins, John F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3159437/
https://www.ncbi.nlm.nih.gov/pubmed/21525127
http://dx.doi.org/10.1093/nar/gkr224

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