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The adenovirus E4orf4 protein targets PP2A to the ACF chromatin-remodeling factor and induces cell death through regulation of SNF2h-containing complexes
The adenovirus E4 open-reading-frame 4 (E4orf4) protein regulates the progression of viral infection and when expressed individually it induces non-classical apoptosis in transformed cells. Here we show that E4orf4 associates with the ATP-dependent chromatin-remodeling factor ACF that consists of a...
Autores principales: | Brestovitsky, Anna, Sharf, Rakefet, Mittelman, Karin, Kleinberger, Tamar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3159439/ https://www.ncbi.nlm.nih.gov/pubmed/21546548 http://dx.doi.org/10.1093/nar/gkr231 |
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