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SHAPE analysis of the FIV Leader RNA reveals a structural switch potentially controlling viral packaging and genome dimerization

Feline immunodeficiency virus (FIV) infects many species of cat, and is related to HIV, causing a similar pathology. High-throughput selective 2′ hydroxyl acylation analysed by primer extension (SHAPE), a technique that allows structural interrogation at each nucleotide, was used to map the secondar...

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Detalles Bibliográficos
Autores principales: Kenyon, Julia C., Tanner, Sian J., Legiewicz, Michal, Phillip, Pretty S., Rizvi, Tahir A., Le Grice, Stuart F. J., Lever, Andrew M. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3159445/
https://www.ncbi.nlm.nih.gov/pubmed/21546549
http://dx.doi.org/10.1093/nar/gkr252