Specific implications of the HIV-1 nucleocapsid zinc fingers in the annealing of the primer binding site complementary sequences during the obligatory plus strand transfer

Synthesis of the HIV-1 viral DNA by reverse transcriptase involves two obligatory strand transfer reactions. The second strand transfer corresponds to the annealing of the (−) and (+) DNA copies of the primer binding site (PBS) sequence which is chaperoned by the nucleocapsid protein (NCp7). NCp7 mo...

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Detalles Bibliográficos
Autores principales: Godet, Julien, Ramalanjaona, Nick, Sharma, Kamal K., Richert, Ludovic, de Rocquigny, Hugues, Darlix, Jean-Luc, Duportail, Guy, Mély, Yves
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3159456/
https://www.ncbi.nlm.nih.gov/pubmed/21543454
http://dx.doi.org/10.1093/nar/gkr274

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