NF-kappaB P50/P65 hetero-dimer mediates differential regulation of CD166/ALCAM expression via interaction with micoRNA-9 after serum deprivation, providing evidence for a novel negative auto-regulatory loop

CD166/ALCAM plays an important role in tumor aggression and progression as well as protecting cancer cells against apoptosis and autophagy. However, the mechanism by which pro-cell death signals control CD166 expression remains unclear. Here we show that following serum deprivation (SD), upregulatio...

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Detalles Bibliográficos
Autores principales: Wang, Jiayi, Gu, Zhidong, Ni, Peihua, Qiao, Yongxia, Chen, Changqiang, Liu, Xiangfan, Lin, Jiafei, Chen, Ning, Fan, Qishi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Gene Regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3159468/
https://www.ncbi.nlm.nih.gov/pubmed/21572107
http://dx.doi.org/10.1093/nar/gkr302

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3159468/
https://www.ncbi.nlm.nih.gov/pubmed/21572107
http://dx.doi.org/10.1093/nar/gkr302

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