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Tracking epigenetic histone modifications in single cells using Fab-based live endogenous modification labeling
Histone modifications play an important role in epigenetic gene regulation and genome integrity. It remains largely unknown, however, how these modifications dynamically change in individual cells. By using fluorescently labeled specific antigen binding fragments (Fabs), we have developed a general...
Autores principales: | Hayashi-Takanaka, Yoko, Yamagata, Kazuo, Wakayama, Teruhiko, Stasevich, Timothy J., Kainuma, Takashi, Tsurimoto, Toshiki, Tachibana, Makoto, Shinkai, Yoichi, Kurumizaka, Hitoshi, Nozaki, Naohito, Kimura, Hiroshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3159477/ https://www.ncbi.nlm.nih.gov/pubmed/21576221 http://dx.doi.org/10.1093/nar/gkr343 |
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