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Dynamic modeling of gene expression in prokaryotes: application to glucose-lactose diauxie in Escherichia coli

Coexpression of genes or, more generally, similarity in the expression profiles poses an unsurmountable obstacle to inferring the gene regulatory network (GRN) based solely on data from DNA microarray time series. Clustering of genes with similar expression profiles allows for a course-grained view...

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Detalles Bibliográficos
Autores principales: Albert, Jaroslav, Rooman, Marianne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3159693/
https://www.ncbi.nlm.nih.gov/pubmed/21949674
http://dx.doi.org/10.1007/s11693-011-9079-2