The ten grand challenges of synthetic life

The construction of artificial life is one of the main scientific challenges of the Synthetic Biology era. Advances in DNA synthesis and a better understanding of regulatory processes make the goal of constructing the first artificial cell a realistic possibility. This would be both a fundamental sc...

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Detalles Bibliográficos
Autores principales: Porcar, Manuel, Danchin, Antoine, de Lorenzo, Victor, dos Santos, Vitor A., Krasnogor, Natalio, Rasmussen, Steen, Moya, Andrés
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2011
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3159694/
https://www.ncbi.nlm.nih.gov/pubmed/21949672
http://dx.doi.org/10.1007/s11693-011-9084-5
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author Porcar, Manuel
Danchin, Antoine
de Lorenzo, Victor
dos Santos, Vitor A.
Krasnogor, Natalio
Rasmussen, Steen
Moya, Andrés
author_facet Porcar, Manuel
Danchin, Antoine
de Lorenzo, Victor
dos Santos, Vitor A.
Krasnogor, Natalio
Rasmussen, Steen
Moya, Andrés
author_sort Porcar, Manuel
collection PubMed
description The construction of artificial life is one of the main scientific challenges of the Synthetic Biology era. Advances in DNA synthesis and a better understanding of regulatory processes make the goal of constructing the first artificial cell a realistic possibility. This would be both a fundamental scientific milestone and a starting point of a vast range of applications, from biofuel production to drug design. However, several major issues might hamper the objective of achieving an artificial cell. From the bottom-up to the selection-based strategies, this work encompasses the ten grand challenges synthetic biologists will have to be aware of in order to cope with the task of creating life in the lab.
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spelling pubmed-31596942011-09-21 The ten grand challenges of synthetic life Porcar, Manuel Danchin, Antoine de Lorenzo, Victor dos Santos, Vitor A. Krasnogor, Natalio Rasmussen, Steen Moya, Andrés Syst Synth Biol Commentary The construction of artificial life is one of the main scientific challenges of the Synthetic Biology era. Advances in DNA synthesis and a better understanding of regulatory processes make the goal of constructing the first artificial cell a realistic possibility. This would be both a fundamental scientific milestone and a starting point of a vast range of applications, from biofuel production to drug design. However, several major issues might hamper the objective of achieving an artificial cell. From the bottom-up to the selection-based strategies, this work encompasses the ten grand challenges synthetic biologists will have to be aware of in order to cope with the task of creating life in the lab. Springer Netherlands 2011-08-05 2011-06 /pmc/articles/PMC3159694/ /pubmed/21949672 http://dx.doi.org/10.1007/s11693-011-9084-5 Text en © The Author(s) 2011 https://creativecommons.org/licenses/by-nc/4.0/ This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited.
spellingShingle Commentary
Porcar, Manuel
Danchin, Antoine
de Lorenzo, Victor
dos Santos, Vitor A.
Krasnogor, Natalio
Rasmussen, Steen
Moya, Andrés
The ten grand challenges of synthetic life
title The ten grand challenges of synthetic life
title_full The ten grand challenges of synthetic life
title_fullStr The ten grand challenges of synthetic life
title_full_unstemmed The ten grand challenges of synthetic life
title_short The ten grand challenges of synthetic life
title_sort ten grand challenges of synthetic life
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3159694/
https://www.ncbi.nlm.nih.gov/pubmed/21949672
http://dx.doi.org/10.1007/s11693-011-9084-5
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