Predicting selective drug targets in cancer through metabolic networks

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The interest in studying metabolic alterations in cancer and their potential role as novel targets for therapy has been rejuvenated in recent years. Here, we report the development of the first genome-scale network model of cancer metabolism, validated by correctly identifying genes essential for ce...

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Detalles Bibliográficos
Autores principales: Folger, Ori, Jerby, Livnat, Frezza, Christian, Gottlieb, Eyal, Ruppin, Eytan, Shlomi, Tomer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Molecular Biology Organization 2011
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Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3159974/
https://www.ncbi.nlm.nih.gov/pubmed/21694718
http://dx.doi.org/10.1038/msb.2011.35
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