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In Vivo Induction of Tr1 Cells via Mucosal Dendritic Cells and AHR Signaling

BACKGROUND: Type 1 regulatory T (Tr1) cells, characterized by the secretion of high levels of the anti-inflammatory cytokine interleukin-10 (IL-10), play an important role in the regulation of autoimmune diseases and transplantation. However, effective strategies that specifically induce Tr1 cells i...

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Detalles Bibliográficos
Autores principales: Wu, Henry Yim, Quintana, Francisco J., da Cunha, Andre Pires, Dake, Benjamin T., Koeglsperger, Thomas, Starossom, Sarah C., Weiner, Howard L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3160310/
https://www.ncbi.nlm.nih.gov/pubmed/21886804
http://dx.doi.org/10.1371/journal.pone.0023618