Transduction of SIV-Specific TCR Genes into Rhesus Macaque CD8(+) T Cells Conveys the Ability to Suppress SIV Replication

BACKGROUND: The SIV/rhesus macaque model for HIV/AIDS is a powerful system for examining the contribution of T cells in the control of AIDS viruses. To better our understanding of CD8(+) T-cell control of SIV replication in CD4(+) T cells, we asked whether TCRs isolated from rhesus macaque CD8(+) T-...

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Detalles Bibliográficos
Autores principales: Barsov, Eugene V., Trivett, Matthew T., Minang, Jacob T., Sun, Haosi, Ohlen, Claes, Ott, David E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3160320/
https://www.ncbi.nlm.nih.gov/pubmed/21886812
http://dx.doi.org/10.1371/journal.pone.0023703

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3160320/
https://www.ncbi.nlm.nih.gov/pubmed/21886812
http://dx.doi.org/10.1371/journal.pone.0023703

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