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Calcineurin Inhibitor-Induced and Ras-Mediated Overexpression of VEGF in Renal Cancer Cells Involves mTOR through the Regulation of PRAS40

Malignancy is a major problem in patients treated with immunosuppressive agents. We have demonstrated that treatment with calcineurin inhibitors (CNIs) can induce the activation of proto-oncogenic Ras, and may promote a rapid progression of human renal cancer through the overexpression of vascular e...

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Detalles Bibliográficos
Autores principales:	Basu, Aninda, Banerjee, Pallavi, Contreras, Alan G., Flynn, Evelyn, Pal, Soumitro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3160347/ https://www.ncbi.nlm.nih.gov/pubmed/21886838 http://dx.doi.org/10.1371/journal.pone.0023919

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