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Postnatal loss of Dlk1 imprinting in stem cells and niche-astrocytes regulates neurogenesis
The gene for the atypical Notch ligand Delta-like homologue 1 (Dlk1) encodes membrane-bound and secreted isoforms functioning in multiple developmental processes in vitro and in vivo. Dlk1, a member of a cluster of imprinted genes, is expressed from the paternally-inherited chromosome(1,2). Here we...
Autores principales: | Ferrón, Sacri R., Charalambous, Marika, Radford, Elizabeth, McEwen, Kirsten, Wildner, Hendrik, Hind, Eleanor, Morante-Redolat, Jose Manuel, Laborda, Jorge, Guillemot, Francois, Bauer, Steven R., Fariñas, Isabel, Ferguson-Smith, Anne C |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3160481/ https://www.ncbi.nlm.nih.gov/pubmed/21776083 http://dx.doi.org/10.1038/nature10229 |
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