NF-κB Inducing Kinase, NIK Mediates Cigarette Smoke/TNFα-Induced Histone Acetylation and Inflammation through Differential Activation of IKKs

BACKGROUND: Nuclear factor (NF)-κB inducing kinase (NIK) is a central player in the non-canonical NF κB pathway, which phosphorylates IκB kinase α (IKKα) resulting in enhancement of target gene expression. We have recently shown that IKKα responds to a variety of stimuli including oxidants and cigar...

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Detalles Bibliográficos
Autores principales: Chung, Sangwoon, Sundar, Isaac K., Hwang, Jae-Woong, Yull, Fiona E., Blackwell, Timothy S., Kinnula, Vuokko L., Bulger, Michael, Yao, Hongwei, Rahman, Irfan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3160853/
https://www.ncbi.nlm.nih.gov/pubmed/21887257
http://dx.doi.org/10.1371/journal.pone.0023488

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