Critical Role of PI3K/Akt/GSK3β in Motoneuron Specification from Human Neural Stem Cells in Response to FGF2 and EGF

Fibroblast growth factor (FGF) and epidermal growth factor (EGF) are critical for the development of the nervous system. We previously discovered that FGF2 and EGF had opposite effects on motor neuron differentiation from human fetal neural stem cells (hNSCs), but the underlying mechanisms remain un...

Descripción completa

Detalles Bibliográficos
Autores principales: Ojeda, Luis, Gao, Junling, Hooten, Kristopher G., Wang, Enyin, Thonhoff, Jason R., Dunn, Tiffany J., Gao, Tianyan, Wu, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3160859/
https://www.ncbi.nlm.nih.gov/pubmed/21887250
http://dx.doi.org/10.1371/journal.pone.0023414

Ejemplares similares

Ejemplares similares