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The Peptidyl Prolyl Isomerase Rrd1 Regulates the Elongation of RNA Polymerase II during Transcriptional Stresses

Rapamycin is an anticancer agent and immunosuppressant that acts by inhibiting the TOR signaling pathway. In yeast, rapamycin mediates a profound transcriptional response for which the RRD1 gene is required. To further investigate this connection, we performed genome-wide location analysis of RNA po...

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Detalles Bibliográficos
Autores principales: Poschmann, Jeremie, Drouin, Simon, Jacques, Pierre-Etienne, El Fadili, Karima, Newmarch, Michael, Robert, François, Ramotar, Dindial
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3160861/
https://www.ncbi.nlm.nih.gov/pubmed/21887235
http://dx.doi.org/10.1371/journal.pone.0023159