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High Density Lipoprotein Structural Changes and Drug Response in Lipidomic Profiles following the Long-Term Fenofibrate Therapy in the FIELD Substudy

In a recent FIELD study the fenofibrate therapy surprisingly failed to achieve significant benefit over placebo in the primary endpoint of coronary heart disease events. Increased levels of atherogenic homocysteine were observed in some patients assigned to fenofibrate therapy but the molecular mech...

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Detalles Bibliográficos
Autores principales: Yetukuri, Laxman, Huopaniemi, Ilkka, Koivuniemi, Artturi, Maranghi, Marianna, Hiukka, Anne, Nygren, Heli, Kaski, Samuel, Taskinen, Marja-Riitta, Vattulainen, Ilpo, Jauhiainen, Matti, Orešič, Matej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3160907/
https://www.ncbi.nlm.nih.gov/pubmed/21887280
http://dx.doi.org/10.1371/journal.pone.0023589