Bone morphogenetic protein-2 functions as a negative regulator in the differentiation of myoblasts, but not as an inducer for the formations of cartilage and bone in mouse embryonic tongue

BACKGROUND: In vitro studies using the myogenic cell line C2C12 demonstrate that bone morphogenetic protein-2 (BMP-2) converts the developmental pathway of C2C12 from a myogenic cell lineage to an osteoblastic cell lineage. Further, in vivo studies using null mutation mice demonstrate that BMPs inhi...

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Detalles Bibliográficos
Autores principales: Aoyama, Kayoko, Yamane, Akira, Suga, Takeo, Suzuki, Erika, Fukui, Tadayoshi, Nakamura, Yoshiki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3160908/
https://www.ncbi.nlm.nih.gov/pubmed/21736745
http://dx.doi.org/10.1186/1471-213X-11-44

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