CK2 Phosphorylation of Schistosoma mansoni HMGB1 Protein Regulates Its Cellular Traffic and Secretion but Not Its DNA Transactions

BACKGROUND: The helminth Schistosoma mansoni parasite resides in mesenteric veins where fecundated female worms lay hundred of eggs daily. Some of the egg antigens are trapped in the liver and induce a vigorous granulomatous response. High Mobility Group Box 1 (HMGB1), a nuclear factor, can also be...

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Detalles Bibliográficos
Autores principales: de Abreu da Silva, Isabel Caetano, Carneiro, Vitor Coutinho, Maciel, Renata de Moraes, da Costa, Rodrigo Furtado Madeiro, Furtado, Daniel Rodrigues, de Oliveira, Francisco Meirelles Bastos, da Silva-Neto, Mário Alberto Cardoso, Rumjanek, Franklin David, Fantappié, Marcelo Rosado
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3160966/
https://www.ncbi.nlm.nih.gov/pubmed/21887276
http://dx.doi.org/10.1371/journal.pone.0023572

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