Cargando…

Stops making sense: translational trade-offs and stop codon reassignment

BACKGROUND: Efficient gene expression involves a trade-off between (i) premature termination of protein synthesis; and (ii) readthrough, where the ribosome fails to dissociate at the terminal stop. Sense codons that are similar in sequence to stop codons are more susceptible to nonsense mutation, an...

Descripción completa

Detalles Bibliográficos
Autores principales:	Johnson, Louise J, Cotton, James A, Lichtenstein, Conrad P, Elgar, Greg S, Nichols, Richard A, Polly, p David, Le Comber, Steven C
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3161013/ https://www.ncbi.nlm.nih.gov/pubmed/21801361 http://dx.doi.org/10.1186/1471-2148-11-227

Ejemplares similares

Selection for tandem stop codons in ciliate species with reassigned stop codons
por: Fleming, Ira, et al.
Publicado: (2019)

Stop or Not: Genome-Wide Profiling of Reassigned Stop Codons in Ciliates
por: Chen, Wenbing, et al.
Publicado: (2023)

Novel Ciliate Genetic Code Variants Including the Reassignment of All Three Stop Codons to Sense Codons in Condylostoma magnum
por: Heaphy, Stephen M., et al.
Publicado: (2016)

Dissecting the Contribution of Release Factor Interactions to Amber Stop Codon Reassignment Efficiencies of the Methanocaldococcus jannaschii Orthogonal Pair
por: Schwark, David G., et al.
Publicado: (2018)

Stop Codon Context-Specific Induction of Translational Readthrough
por: Schilff, Mirco, et al.
Publicado: (2021)

Stops making sense – For the people?
por: Valášek, Leoš Shivaya, et al.
Publicado: (2023)

A reporter system for translational readthrough of stop codons in human cells
por: Halvey, Patrick J., et al.
Publicado: (2012)

Genetic Codes with No Dedicated Stop Codon: Context-Dependent Translation Termination
por: Swart, Estienne Carl, et al.
Publicado: (2016)

Translational read-through promotes aggregation and shapes stop codon identity
por: Kramarski, Lior, et al.
Publicado: (2020)

Conservation of tandem stop codons in yeasts
por: Liang, Han, et al.
Publicado: (2005)

Stop codons in bacteria are not selectively equivalent
por: Povolotskaya, Inna S, et al.
Publicado: (2012)

Natural reassignment of CUU and CUA sense codons to alanine in Ashbya mitochondria
por: Ling, Jiqiang, et al.
Publicado: (2014)

Modification of orthogonal tRNAs: unexpected consequences for sense codon reassignment
por: Biddle, Wil, et al.
Publicado: (2016)

Translation initiation factor eIF3 promotes programmed stop codon readthrough
por: Beznosková, Petra, et al.
Publicado: (2015)

Widespread stop-codon recoding in bacteriophages may regulate translation of lytic genes
por: Borges, Adair L., et al.
Publicado: (2022)

Evolutionary Dynamics of Abundant Stop Codon Readthrough
por: Jungreis, Irwin, et al.
Publicado: (2016)

Purifying and positive selection in the evolution of stop codons
por: Belinky, Frida, et al.
Publicado: (2018)

The Mechanisms of Codon Reassignments in Mitochondrial Genetic Codes
por: Sengupta, Supratim, et al.
Publicado: (2007)

Codon reassignment in the Escherichia coli genetic code
por: Mukai, Takahito, et al.
Publicado: (2010)

ATP hydrolysis by UPF1 is required for efficient translation termination at premature stop codons
por: Serdar, Lucas D., et al.
Publicado: (2016)

PABP enhances release factor recruitment and stop codon recognition during translation termination
por: Ivanov, Alexandr, et al.
Publicado: (2016)

Enabling stop codon read-through translation in bacteria as a probe for amyloid aggregation
por: Molina-García, Laura, et al.
Publicado: (2017)

Impact of queuosine modification of endogenous E. coli tRNAs on sense codon reassignment
por: Tittle, Jillyn M., et al.
Publicado: (2022)

Selective forces and mutational biases drive stop codon usage in the human genome: a comparison with sense codon usage
por: Trotta, Edoardo
Publicado: (2016)

Stop making sense or Regulation at the level of termination in eukaryotic protein synthesis
por: Valle, Rosaura P.C., et al.
Publicado: (1988)

Widespread Polymorphism in the Positions of Stop Codons in Drosophila melanogaster
por: Lee, Yuh Chwen G., et al.
Publicado: (2012)

Identification of stop codon readthrough genes in Saccharomyces cerevisiae
por: Namy, Olivier, et al.
Publicado: (2003)

Evidence of efficient stop codon readthrough in four mammalian genes
por: Loughran, Gary, et al.
Publicado: (2014)

Designing logical codon reassignment – Expanding the chemistry in biology
por: Dumas, Anaëlle, et al.
Publicado: (2015)

Ribosome Rescue and Translation Termination at Non-Standard Stop Codons by ICT1 in Mammalian Mitochondria
por: Akabane, Shiori, et al.
Publicado: (2014)

Human mitochondria require mtRF1 for translation termination at non-canonical stop codons
por: Krüger, Annika, et al.
Publicado: (2023)

Reassignment of a rare sense codon to a non-canonical amino acid in Escherichia coli
por: Mukai, Takahito, et al.
Publicado: (2015)

Oligonucleotide-mediated tRNA sequestration enables one-pot sense codon reassignment in vitro
por: Cui, Zhenling, et al.
Publicado: (2018)

MACSE: Multiple Alignment of Coding SEquences Accounting for Frameshifts and Stop Codons
por: Ranwez, Vincent, et al.
Publicado: (2011)

Stop codon context influences genome-wide stimulation of termination codon readthrough by aminoglycosides
por: Wangen, Jamie R, et al.
Publicado: (2020)

Stop! Stop!
Publicado: (1913)

The sense of stopping migraine prophylaxis
por: Al-Hassany, Linda, et al.
Publicado: (2023)

Heterologous Stop Codon Readthrough of Metazoan Readthrough Candidates in Yeast
por: Chan, Clara S., et al.
Publicado: (2013)

Human SNPs resulting in premature stop codons and protein truncation
por: Savas, Sevtap, et al.
Publicado: (2006)

New insights into stop codon recognition by eRF1
por: Blanchet, Sandra, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_ksepek6a8bul01cdh0f5b76vph