Cargando…

Sphingosine Kinase 1 and Sphingosine 1-Phosphate Receptor 3 Are Functionally Upregulated on Astrocytes under Pro-Inflammatory Conditions

BACKGROUND: Reactive astrocytes are implicated in the development and maintenance of neuroinflammation in the demyelinating disease multiple sclerosis (MS). The sphingosine kinase 1 (SphK1)/sphingosine1-phosphate (S1P) receptor signaling pathway is involved in modulation of the inflammatory response...

Descripción completa

Detalles Bibliográficos
Autores principales:	Fischer, Iris, Alliod, Chantal, Martinier, Nicolas, Newcombe, Jia, Brana, Corinne, Pouly, Sandrine
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3161076/ https://www.ncbi.nlm.nih.gov/pubmed/21887342 http://dx.doi.org/10.1371/journal.pone.0023905

Ejemplares similares

Interaction of microRNAs with sphingosine kinases, sphingosine-1 phosphate, and sphingosine-1 phosphate receptors in cancer
por: Xu, Guangmeng, et al.
Publicado: (2021)

Sphingosine Kinase 1 and Sphingosine-1-Phosphate Signaling in Colorectal Cancer
por: Bao, Yonghua, et al.
Publicado: (2017)

Reduced sphingosine kinase-1 and enhanced sphingosine 1-phosphate lyase expression demonstrate deregulated sphingosine 1-phosphate signaling in Alzheimer’s disease
por: Ceccom, Johnatan, et al.
Publicado: (2014)

Sphingosine Kinases/Sphingosine-1-Phosphate and Death Signalling in APP-Transfected Cells
por: Gassowska, Magdalena, et al.
Publicado: (2014)

Characterizing Sphingosine Kinases and Sphingosine 1-Phosphate Receptors in the Mammalian Eye and Retina
por: Porter, Hunter, et al.
Publicado: (2018)

Sphingosine Kinases and Sphingosine 1-Phosphate Receptors: Signaling and Actions in the Cardiovascular System
por: Cannavo, Alessandro, et al.
Publicado: (2017)

Commentary: The sphingosine kinase 1/sphingosine-1-phosphate pathway in pulmonary arterial hypertension
por: Bhavanam, Naga P., et al.
Publicado: (2015)

Impairment of Angiogenic Sphingosine Kinase-1/Sphingosine-1-Phosphate Receptors Pathway in Preeclampsia
por: Dobierzewska, Aneta, et al.
Publicado: (2016)

Regulation of cellular sphingosine-1-phosphate by sphingosine kinase 1 and sphingosine-1-phopshate lyase determines chemotherapy resistance in gastroesophageal cancer
por: Matula, Kasia, et al.
Publicado: (2015)

The Role of Sphingolipids and Sphingosine-1-phosphate—Sphingosine-1-phosphate-receptor Signaling in Psoriasis
por: Masuda-Kuroki, Kana, et al.
Publicado: (2023)

Sphingosine Kinase Expression Increases Intracellular Sphingosine-1-Phosphate and Promotes Cell Growth and Survival
por: Olivera, Ana, et al.
Publicado: (1999)

Regulatory role of sphingosine kinase and sphingosine-1-phosphate receptor signaling in progenitor/stem cells
por: Ng, Mei Li, et al.
Publicado: (2018)

Targeting the Sphingosine Kinase/Sphingosine-1-Phosphate Signaling Axis in Drug Discovery for Cancer Therapy
por: Gupta, Preeti, et al.
Publicado: (2021)

The Role of Sphingosine Kinase 1/Sphingosine-1-Phosphate Pathway in the Myogenic Tone of Posterior Cerebral Arteries
por: Lim, Mihwa, et al.
Publicado: (2012)

Sphingosine kinase and sphingosine-1-phosphate regulate epithelial cell architecture by the modulation of de novo sphingolipid synthesis
por: Santacreu, Bruno Jaime, et al.
Publicado: (2019)

Sphingosine 1-Phosphate and Atherosclerosis
por: Kurano, Makoto, et al.
Publicado: (2018)

Estrogen transactivates EGFR via the sphingosine 1-phosphate receptor Edg-3: the role of sphingosine kinase-1
por: Sukocheva, Olga, et al.
Publicado: (2006)

Sphingosine kinase 1/sphingosine-1-phosphate (S1P)/S1P receptor axis is involved in ovarian cancer angiogenesis
por: Dai, Lan, et al.
Publicado: (2017)

Circulating sphingosine-1-phosphate and erythrocyte sphingosine kinase-1 activity as novel biomarkers for early prostate cancer detection
por: Nunes, J, et al.
Publicado: (2012)

Sphingosine 1-phosphate receptors and sphingosine kinase 1: novel biomarkers for clinical prognosis in breast, prostate, and hematological cancers
por: Pyne, Susan, et al.
Publicado: (2012)

Overexpression of Sphingosine Kinase-1 and Sphingosine-1-Phosphate Receptor-3 in Severe Plasmodium falciparum Malaria with Pulmonary Edema
por: Viriyavejakul, Parnpen, et al.
Publicado: (2020)

Potential of a sphingosine 1-phosphate receptor antagonist and sphingosine kinase inhibitors as targets for multiple myeloma treatment
por: Tanaka, Yuko, et al.
Publicado: (2022)

Role of sphingosine kinase and sphingosine-1-phosphate receptor in the liver pathology of mice infected with Plasmodium berghei ANKA
por: Techarang, Tachpon, et al.
Publicado: (2022)

Sphingosine kinase 1 mediates head & neck squamous cell carcinoma invasion through sphingosine 1-phosphate receptor 1
por: Tamashiro, Paulette M, et al.
Publicado: (2014)

Triple Negative Breast Cancer Depends on Sphingosine Kinase 1 (SphK1)/Sphingosine-1-Phosphate (S1P)/Sphingosine 1-Phosphate Receptor 3 (S1PR3)/Notch Signaling for Metastasis
por: Wang, Shushu, et al.
Publicado: (2018)

Dihydro-sphingosine 1-phosphate interacts with carrier proteins in a manner distinct from that of sphingosine 1-phosphate
por: Mishima, Yuko, et al.
Publicado: (2018)

Irisin Is Target of Sphingosine-1-Phosphate/Sphingosine-1-Phosphate Receptor-Mediated Signaling in Skeletal Muscle Cells
por: Pierucci, Federica, et al.
Publicado: (2023)

Sphingosine kinase 1-associated autophagy differs between neurons and astrocytes
por: Moruno-Manchon, Jose F., et al.
Publicado: (2018)

Sphingosine‐1‐phosphate improves outcome of no‐reflow acute myocardial infarction via sphingosine‐1‐phosphate receptor 1
por: Polzin, Amin, et al.
Publicado: (2022)

Expression of sphingosine 1-phosphate receptor 4 and sphingosine kinase 1 is associated with outcome in oestrogen receptor-negative breast cancer
por: Ohotski, J, et al.
Publicado: (2012)

Expression of sphingosine 1-phosphate receptor 4 and sphingosine kinase 1 is associated with outcome in oestrogen receptor negative breast cancer
por: Ohotski, J, et al.
Publicado: (2012)

Insulin Protects Apoptotic Cardiomyocytes from Hypoxia/Reoxygenation Injury through the Sphingosine Kinase/Sphingosine 1-Phosphate Axis
por: Yu, Huan, et al.
Publicado: (2013)

Flotillin proteins recruit sphingosine to membranes and maintain cellular sphingosine-1-phosphate levels
por: Riento, Kirsi, et al.
Publicado: (2018)

Decreased serum concentrations of sphingosine-1-phosphate in sepsis
por: Winkler, Martin Sebastian, et al.
Publicado: (2015)

Sphingosine 1-phosphate enhances the excitability of rat sensory neurons through activation of sphingosine 1-phosphate receptors 1 and/or 3
por: Li, Chao, et al.
Publicado: (2015)

Sphingosine kinase/sphingosine 1-phosphate axis: a new player for insulin-like growth factor-1-induced myoblast differentiation
por: Bernacchioni, Caterina, et al.
Publicado: (2012)

Targeting sphingosine-1-phosphate for cancer therapy
por: Sabbadini, R A
Publicado: (2006)

Immunological Function of Sphingosine 1-Phosphate in the Intestine
por: Kunisawa, Jun, et al.
Publicado: (2012)

Plasma Sphingosine-1-Phosphate Is Elevated in Obesity
por: Kowalski, Greg M., et al.
Publicado: (2013)

Sphingosine 1-Phosphate in Acute Dengue Infection
por: Gomes, Laksiri, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_4dkhdtg0pkkok6ut9g7dnodtp8