Early Presymptomatic and Long-Term Changes of Rest Activity Cycles and Cognitive Behavior in a MPTP-Monkey Model of Parkinson's Disease

BACKGROUND: It is increasingly recognized that non-motor symptoms are a prominent feature of Parkinson's disease and in the case of cognitive deficits can precede onset of the characteristic motor symptoms. Here, we examine in 4 monkeys chronically treated with low doses of the neurotoxin MPTP...

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Detalles Bibliográficos
Autores principales: Vezoli, Julien, Fifel, Karim, Leviel, Vincent, Dehay, Colette, Kennedy, Henry, Cooper, Howard M., Gronfier, Claude, Procyk, Emmanuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3161087/
https://www.ncbi.nlm.nih.gov/pubmed/21887350
http://dx.doi.org/10.1371/journal.pone.0023952

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