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Ketamine Influences CLOCK:BMAL1 Function Leading to Altered Circadian Gene Expression

Major mood disorders have been linked to abnormalities in circadian rhythms, leading to disturbances in sleep, mood, temperature, and hormonal levels. We provide evidence that ketamine, a drug with rapid antidepressant effects, influences the function of the circadian molecular machinery. Ketamine m...

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Detalles Bibliográficos
Autores principales: Bellet, Marina M., Vawter, Marquis P., Bunney, Blynn G., Bunney, William E., Sassone-Corsi, Paolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3161090/
https://www.ncbi.nlm.nih.gov/pubmed/21887357
http://dx.doi.org/10.1371/journal.pone.0023982