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C-KIT Signaling Depends on Microphthalmia-Associated Transcription Factor for Effects on Cell Proliferation
The development of melanocytes is regulated by the tyrosine kinase receptor c-KIT and the basic-helix-loop-helix-leucine zipper transcription factor Mitf. These essential melanocyte survival regulators are also well known oncogenic factors in malignant melanoma. Despite their importance, not much is...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3161112/ https://www.ncbi.nlm.nih.gov/pubmed/21887372 http://dx.doi.org/10.1371/journal.pone.0024064 |