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C-KIT Signaling Depends on Microphthalmia-Associated Transcription Factor for Effects on Cell Proliferation

The development of melanocytes is regulated by the tyrosine kinase receptor c-KIT and the basic-helix-loop-helix-leucine zipper transcription factor Mitf. These essential melanocyte survival regulators are also well known oncogenic factors in malignant melanoma. Despite their importance, not much is...

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Detalles Bibliográficos
Autores principales: Phung, Bengt, Sun, Jianmin, Schepsky, Alexander, Steingrimsson, Eirikur, Rönnstrand, Lars
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3161112/
https://www.ncbi.nlm.nih.gov/pubmed/21887372
http://dx.doi.org/10.1371/journal.pone.0024064